Course addresses management and engineering design concepts required for process safety in chemical and biotechnology systems, with pharmaceutical manufacturing applications. Basis is Process Safety Management (PSM) model from OSHA and the Center for Chemical Process Safety of AIChE. Content focuses on sound engineering principles and practices as they apply to industrial situations, project design, risk mitigation, process and equipment integrity, and engineering codes and standards. Includes calculation of risk assessment scores and cost justification factor; HAZOPs studies using P&IDs; sizing safety valves, rupture discs, explosion venting, and emergency scrubbers; MSDS applied to dispersion modeling; overall control, reduction, and prevention of hazardous materials incidents; case studies.
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